Brandon Aiyuk's acceleration and ball-tracking skills could spell trouble for Kansas City's middling safeties, but first the Niners need to keep DL Chris Jones off of Brock Purdy.
Everyone agrees that Lamar Jackson needs to be blitzed, but just how much pressure should the Chiefs bring this Sunday?
The Chiefs' passing game has mostly been disappointing this year, but Rashee Rice and Travis Kelce both played well last week and now face a banged-up Buffalo secondary in the divisional round.
Facing a tough defense with the bull's eye on him, Sunday's showdown with Buffalo will help clarify just how good Rashee Rice can be.
CeeDee Lamb could have one of his biggest games playing against a Lions defense that's tougher against the run than the pass.
Juan Carlos Blanco has you covered on the latest Sunday morning Week 15 injury news as the fantasy playoffs kick off in many leagues.
Tyreek Hill and De'Von Achane both are questionable, and their numbers might disappoint even if they play given Miami's slew of injury concerns along the offensive line.
If New England prioritizes defending Travis Kelce then the Pats might not have leftover personnel to cover Rashee Rice.
Rashee Rice can be locked in as an every-week fantasy starter after topping 80% snap share for the first time in his young career.
The Saints are tougher on the boundary than in the slot, which should provoke a big game from Amon-Ra St. Brown.
CeeDee Lamb has been a menace from the slot, where Washington lacks the coverage personnel to defend itself.
Playing at home and against the Bears, the Week 11 setup couldn't be much easier for Amon-Ra St. Brown.
DeAndre Hopkins should be able to get rolling against a struggling and injured Tampa Bay corner rotation.
Nico Collins and Tank Dell should come roaring out of the bye week against a battered and weak Carolina secondary.